A person who has adrenal insufficiency should always carry identification stating his or her condition in case of an emergency. The card should alert emergency personnel about the need to inject 100 mg of cortisol if its bearer is found severely injured or unable to answer questions. The card should also include the doctors name and telephone number and the name and telephone number of the nearest relative to be notified. When traveling, it is important to have a needle, syringe, and an injectable form of cortisol for emergencies. A person with Addisons disease also should know how to increase medication during periods of stress or mild upper respiratory infections. Immediate medical attention is needed when severe infections or vomiting or diarrhea occur. These conditions can precipitate an addisonian crisis. A patient who is vomiting may require injections of hydrocortisone.
Another well-controlled clinical study evaluated 279 subjects with mild to moderate plaque-type psoriasis (mean Body Surface Area at baseline was % with a range from 1% to 20%) of non-scalp regions. Subjects were treated twice daily for 2 weeks with OLUX (clobetasol propionate) Foam or Vehicle foam. The face and intertriginous areas were excluded from treatment. The efficacy of OLUX (clobetasol propionate) Foam in treating non-scalp psoriasis at the end of 2 weeks' treatment was superior to that of Vehicle foam. See Table 2 below.
Clobetasol propionate is a man-made corticosteroid that is used on the skin (topically). It is available as foam, shampoo, cream, gel, lotion, ointment, solution, and spray. It is similar to alclometasone (Aclovate), hydrocortisone valerate (Westcort), halobetasol ( Ultravate ) and several others. Topical clobetasol is used to treat certain scalp and skin conditions such as psoriasis , rashes, and dermatitis . Corticosteroids have potent anti-inflammatory actions and also suppress the immune response. Clobetasol is a very potent topical corticosteroid and should only be used for a short period of time. Long term use of topical clobetasol propionate can cause serious systemic side effects and should be avoided.